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| ALMEIDA,MACIA C.S. DE; SOUZA,LUCIANA G.S.; FERREIRA,DANIELE A.; PINTO,FRANCISCO C.L.; OLIVEIRA,DÉBORA R. DE; SANTIAGO,GILVANDETE M.P.; MONTE,FRANCISCO J.Q.; BRAZ-FILHO,RAIMUNDO; LEMOS,TELMA L.G. DE. |
| ABSTRACT A new lactone, 7-epi-griffonilide (1), and six known compounds, 2, 3a - 3c, 4a and 4b, were isolated from the leaves of Bauhinia pentandra (Fabaceae). The structures elucidation of 1 and 2 were based on detailed 2D NMR techniques and spectral comparison with related compounds, leading to complete assignment of the 1H and 13C NMR spectra. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bauhinia pentandra; Fabaceae; Cyanoglucoside; Lactones; RMN.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100065 |
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| RICARTE,LARA P.; BEZERRA,GABRIELI P.; ROMERO,NIRLA R.; SILVA,HORLANDO C. DA; LEMOS,TELMA L.G.; ARRIAGA,ANGELA M. C.; ALVES,PÉRICLES B.; SANTOS,MARCELO B. DOS; MILITÃO,GARDENIA C.G.; SILVA,THIAGO D.S.; BRAZ-FILHO,RAIMUNDO; SANTIAGO,GILVANDETE M.P.. |
| Abstract The essential oils obtained by hydrodistillation from fresh leaves of Vitex agnus-castus and Ocimum campechianum, and from fresh inflorescences of Ocimum carnosum were analysed by GC-FID and GC-MS. The major components of V. agnus-castus essential oil were identified as 1,8-cineole (47.9%), terpinyl α-acetate (11.6%), sabinene (11.2%) and caryophyllene oxide (9.7%), while in the O. campechianum essential oil were eugenol (72.1%), β-elemene (6.8%), (E)-caryophyllene (6.4%) and bicyclogermacrene (5.2%). Linalool (79.0%), α-epi-cadinol (5.4%), terpinen-4-ol (3.2%) and 1,8-cineole (2.8%) were the major constituents in the O. carnosum essential oil. The essential oils were subsequently evaluated for their larvicidal and cytotoxic activities. Larval... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aedes aegypti; Cytotoxic activity; Lamiaceae; Larvicidal activity. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100718 |
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| OLIVEIRA,MAILCAR F.; LEMOS,TELMA L.G.; MATTOS,MARCOS C. DE; SEGUNDO,TACIANA A.; SANTIAGO,GILVANDETE M.P.; BRAZ-FILHO,RAIMUNDO. |
| A convenient synthesis of the new enamine derivatives 2-(4-morpholinyl)-3-(3-methyl-2-butenyl)-1,4-naphthalenedione, 2-(1-piperidinyl)-3-(3-methyl-2-butenyl)-1,4-naphtalenedione and 2-(1-pyrrolidinyl)-3-(3-methyl-2-butenyl)-1,4-naphthalenedione was carried out from natural 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione (lapachol) and morpholine, piperidine and pyrrolidine. The structures of the products were established mainly by NMR analysis, including 2D experiments. Biological activities of these products were evaluated against Artemia salina, Aedes aegypti and cytotoxicity using A549 human breast cells. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lapachol; Enamine derivatives; Biological activities. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000200004 |
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